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Company Analysis

Upstream Bio, Inc. UPB

A comprehensive view of key metrics, scores, and financial health for Upstream Bio, Inc.

Overview of Upstream Bio, Inc.

UPB NMS
Healthcare Biotechnology Small Cap
Upstream Bio, Inc. (UPB), is a Small Cap company, in the Biotechnology industry, last closed at $9.23, about 0.0% overvalued vs fair value, -6.5% 1Y return, ranked 435/1110 in sector.
$9.23
-2.17%
As of March 13, 2026
Previous close • Vol 90d: 143.9%
52-Week Range
Market Cap
$413.94M
Enterprise Value
$343.19M
Overall Score
Scores locked

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Top Beats
No strong beats yet

Quick Facts

Website https://upstreambio.com
HQ Waltham, MA
Employees 52
Fiscal year Dec 31

Next Events

No upcoming events available.

Fair Value Snapshot

Bear Base Bull
$-2
$-2
$-2
Current: $9.23

Engine Room Money Flow™

Small Cap

Biotech / Pre-Revenue - Where revenue goes and how value is created

Flow Steps
Cash on Hand
$325.9M
1161.5%%
Total Revenue
$2.4M
-0.4%%
Net Income
$-62.8M
-205.8%%
Operating Expense
$80.1M
88.6%%
Money Flow Bridge
Flow Direction: Money moves from left to right
Components: Breakdown shows composition of each stage
Industry-Specific: Biotech / Pre-Revenue

Quality & Reliability Indicators

Cash Runway
66.1 months
Excellent

Strong cash position with 2+ years of runway

Locked Metric
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Where It Leaks

Cash Flow Health healthy
Strong cash conversion with minimal leakage across profit-to-cash-to-value chain.
0
Active Leaks
0/0
Improving
0
High Impact
0
Critical
Moat Analysis Corporate Default

Competitive Advantage Assessment

Evaluating Upstream Bio, Inc.'s durable competitive advantages across 6 defense dimensions

Overall Moat Strength
48
/100
Developing
Scores based on quantitative metrics and qualitative factors

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Pricing Power

Moderate
57
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Trade-Off Ledger

Where management spends the performance budget

Insufficient Data for Analysis

UPB - Upstream Bio, Inc.

We have limited financial data for UPB. The Growth and Profitability axes don't have enough metrics for reliable analysis.

Data Coverage by Axis

Growth
0% coverage Below threshold
Profitability
0% coverage N/A
Overall Coverage: 26.7% (Minimum 40% required)

What This Means

  • Currently at 26.7% data coverage (minimum 40% required)
  • Limited peer data available for industry benchmarking
  • Check back after quarterly or annual filings
  • Some metrics may not be applicable to this company's business model

What can you do?

  • View available sections like Moat Map or Engine Room for partial insights
  • Set up a watchlist alert to be notified when new data becomes available
  • Compare with peers in the same industry that have complete data

Two Futures

Scenario-based fair value ranges for Upstream Bio, Inc..

Loading valuation model...
Unable to Compute Fair Value

This company cannot be valued using standard models.

What this means: The Scenario Theatre requires financial data (revenue, cash flow, shares outstanding) to calculate fair value estimates. This data may be unavailable for:

  • Recently listed companies (IPOs, SPACs)
  • Shell companies or holding companies
  • Companies that haven't filed recent financials
  • Foreign companies with limited data coverage
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Bear
-
- - -
- upside
-
Base
$-2.15
- - -
- upside
Snapshot base estimate
Bull
-
- - -
- upside
-
Fair Value Range Current: $-
$- $- $-
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