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Company Analysis

Denali Therapeutics Inc. DNLI

A comprehensive view of key metrics, scores, and financial health for Denali Therapeutics Inc.

Overview of Denali Therapeutics Inc.

DNLI NMS
Healthcare Biotechnology Mid Cap
Denali Therapeutics Inc. (DNLI), is a Mid Cap company, in the Biotechnology industry, last closed at $18.60, about 0.0% overvalued vs fair value, +11.7% 1Y return, ranked 490/1121 in sector.
Metrics ROE -45.7%
$18.60
-7.28%
As of April 29, 2026
Previous close • Vol 90d: 61.2%
52-Week Range
Market Cap
$3.18B
Enterprise Value
$3.01B
Overall Score
View breakdown
Overall
Growth
Weak
Profitability
Good
Health
Fair
Efficiency
Fair
Valuation
Fair
Growth
Weak
Profitability
Good
Health
Fair
Efficiency
Fair
Valuation
Fair
Completeness: 82%
Confidence: 50%
Updated: Mar 8
Top Beats
No strong beats yet

Quick Facts

Website https://www.denalitherapeutics...
HQ South San Francisco, CA
Employees 517
Fiscal year Dec 31

Next Events

Earnings May 11 Estimated

Fair Value Snapshot

Insufficient data
Show more details
  • Revenue data missing or non-positive

Engine Room Money Flow™

Mid Cap

Biotech / Pre-Revenue - Where revenue goes and how value is created

Flow Steps
Cash on Hand
$205.3M
17.4%%
Total Revenue
$0
-100%%
Net Income
$-512.5M
-21.2%%
Operating Expense
$555.3M
10.7%%
Money Flow Bridge
Flow Direction: Money moves from left to right
Components: Breakdown shows composition of each stage
Industry-Specific: Biotech / Pre-Revenue

Quality & Reliability Indicators

Cash Runway
6.0 months
Poor

Critical: Cash runway under 12 months

Locked Metric
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Owner's Pocket - Capital Allocation

Total Returned to Shareholders

Combined dividends, buybacks, and debt reduction

$19.3M
9.4% of Cash on Hand

Where It Leaks

Cash Flow Health healthy
Strong cash conversion with minimal leakage across profit-to-cash-to-value chain.
0
Active Leaks
0/0
Improving
0
High Impact
0
Critical
Moat Analysis Corporate Default

Competitive Advantage Assessment

Evaluating Denali Therapeutics Inc.'s durable competitive advantages across 6 defense dimensions

Overall Moat Strength
70
/100
Moderate
Scores based on quantitative metrics and qualitative factors

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Pricing Power

Strong
78
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Trade-Off Ledger

Where management spends the performance budget

Insufficient Data for Analysis

DNLI - Denali Therapeutics Inc.

We have limited financial data for DNLI. The Growth and Profitability axes don't have enough metrics for reliable analysis.

Data Coverage by Axis

Growth
0% coverage Below threshold
Profitability
0% coverage N/A
Overall Coverage: 33.3% (Minimum 40% required)

What This Means

  • Currently at 33.3% data coverage (minimum 40% required)
  • Limited peer data available for industry benchmarking
  • Check back after quarterly or annual filings
  • Some metrics may not be applicable to this company's business model

What can you do?

  • View available sections like Moat Map or Engine Room for partial insights
  • Set up a watchlist alert to be notified when new data becomes available
  • Compare with peers in the same industry that have complete data

Two Futures

Scenario-based fair value ranges for Denali Therapeutics Inc..

Loading valuation model...
Unable to Compute Fair Value

This company cannot be valued using standard models.

What this means: The Scenario Theatre requires financial data (revenue, cash flow, shares outstanding) to calculate fair value estimates. This data may be unavailable for:

  • Recently listed companies (IPOs, SPACs)
  • Shell companies or holding companies
  • Companies that haven't filed recent financials
  • Foreign companies with limited data coverage
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Fair Value Range Current: $-
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