Aptose Biosciences, Inc. APTO

Competitive advantage analysis · healthcare

Corporate Default
Overall moat score
28/100
Developing

Ranked against 712 peers in Biotechnology

Key risks

  • ROIC Below WACC or Peers ROIC at 0th percentile suggests inefficient capital deployment.
  • Liquidity Concerns Liquidity is concerning (score 0.24), raising questions about short-term obligations.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

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Pricing Power

Insufficient Data
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Signals, strengths and risks for Pricing Power

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Signals, strengths and risks for Cost Advantage

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Signals, strengths and risks for Customer Stickiness

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Signals, strengths and risks for Capital Efficiency

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Signals, strengths and risks for Resilience

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Signals, strengths and risks for Scale & Market Position

Where APTO ranks in Biotechnology

Aptose Biosciences, Inc. ranks #529 of 713 scored companies in Biotechnology by moat score — the top 74%. The widest moat in the group is Royalty Pharma plc (RPRX) at 85/100.

# Company Moat score Rating
525 Moleculin Biotech, Inc. MBRX 29/100 Developing
526 Forte Biosciences, Inc. FBRX 29/100 Developing
527 Pluri Inc. PLUR 28/100 Developing
528 Alumis Inc. ALMS 28/100 Developing
529 Aptose Biosciences, Inc. APTO 28/100 Developing
530 Entera Bio Ltd. ENTX 28/100 Developing
531 XORTX Therapeutics Inc. XRTX 28/100 Developing
532 Lexeo Therapeutics, Inc. LXEO 28/100 Developing
533 Altimmune, Inc. ALT 28/100 Developing

See every Biotech / Pre-Revenue company ranked by moat score →

How APTO scores on the Corporate Default defenses

Pricing Power

Not measurable · 20% of the moat score

Pricing power is the ability to raise prices without losing volume.

Cost Advantage

Not measurable · 15% of the moat score

A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.

Customer Stickiness

Not measurable · 15% of the moat score

Stickiness is what makes revenue repeat without being re-won every year.

Capital Efficiency

Score 19 · 18% of the moat score

Capital efficiency asks what the company earns on the money tied up in the business.

Resilience

Score 35 · 17% of the moat score

Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.

Scale & Market Position

Not measurable · 15% of the moat score

Scale matters only when it converts into economics.

How each Corporate Default defense is measured, in full →

Understanding APTO's moat

What is Aptose Biosciences, Inc.'s moat score?

Aptose Biosciences, Inc. (APTO) scores 28 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as developing. It ranks #529 of 713 scored companies in Biotechnology, the top 74%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Resilience (35/100) and its weakest is Capital Efficiency (19/100).

How does Aptose Biosciences, Inc. compare with other Biotechnology companies?

Aptose Biosciences, Inc. ranks #529 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Alumis Inc. (ALMS) at 28 just above it and Entera Bio Ltd. (ENTX) at 28 just below it.

How is the moat score calculated?

Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.

Why is Aptose Biosciences, Inc. scored with the Corporate Default template?

Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.

Which competitive defenses are measured for Aptose Biosciences, Inc.?

The Corporate Default template measures 6 defenses, and APTO scores: Pricing Power (not measurable), Cost Advantage (not measurable), Customer Stickiness (not measurable), Capital Efficiency (19), Resilience (35), Scale & Market Position (not measurable). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.

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