Exelixis, Inc. EXEL

Competitive advantage analysis · healthcare

Corporate Default
Overall moat score
82/100
Strong

About Exelixis, Inc.

Exelixis, Inc., an oncology company, focuses on the discovery, development, and commercialization of new medicines for difficult-to-treat cancers in the United States. The company offers CABOMETYX tablets for the treatment of patients with advanced renal cell carcinoma who received prior anti-angiogenic therapy; and COMETRIQ capsules for the treatment of progressive and metastatic medullary thyroid cancer. Its CABOMETYX and COMETRIQ are … Full EXEL analysis →

Competitive advantage assessment

Key strengths

  • Margins Stable Across Cycles Operating margin volatility is low (stability score 0.97), demonstrating pricing resilience across cycles.
  • ROIC Sustainably Above Peers ROIC at 89.9th percentile exceeds peers and WACC, demonstrating superior capital allocation.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

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Pricing Power

Strong
85

Where EXEL ranks in Biotechnology

Exelixis, Inc. ranks #5 of 713 scored companies in Biotechnology by moat score — the top 1%. The widest moat in the group is Royalty Pharma plc (RPRX) at 85/100.

Moat scores for companies ranked near EXEL in Biotechnology
# Company Moat score Rating
1 Royalty Pharma plc RPRX 85/100 Strong
2 Black Diamond Therapeutics, Inc BDTX 84/100 Strong
3 United Therapeutics Corporation UTHR 84/100 Strong
4 Catalyst Pharmaceuticals, Inc. CPRX 83/100 Strong
5 Exelixis, Inc. EXEL 82/100 Strong
6 Incyte Corporation INCY 82/100 Strong
7 Innoviva, Inc. INVA 82/100 Strong
8 Vertex Pharmaceuticals Incorpor VRTX 81/100 Strong
9 Harmony Biosciences Holdings, I HRMY 80/100 Strong

See every Biotech / Pre-Revenue company ranked by moat score →

How EXEL scores on the Corporate Default defenses

Pricing Power

Score 85 · 20% of the moat score

Pricing power is the ability to raise prices without losing volume.

Cost Advantage

Score 95 · 15% of the moat score

A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.

Customer Stickiness

Score 94 · 15% of the moat score

Stickiness is what makes revenue repeat without being re-won every year.

Capital Efficiency

Score 88 · 18% of the moat score

Capital efficiency asks what the company earns on the money tied up in the business.

Resilience

Score 65 · 17% of the moat score

Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.

Scale & Market Position

Score 68 · 15% of the moat score

Scale matters only when it converts into economics.

How each Corporate Default defense is measured, in full →

Understanding EXEL's moat

What is Exelixis, Inc.'s moat score?

Exelixis, Inc. (EXEL) scores 82 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as strong. It ranks #5 of 713 scored companies in Biotechnology, the top 1%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Cost Advantage (95/100) and its weakest is Resilience (65/100).

How does Exelixis, Inc. compare with other Biotechnology companies?

Exelixis, Inc. ranks #5 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Catalyst Pharmaceuticals, Inc. (CPRX) at 83 just above it and Incyte Corporation (INCY) at 82 just below it.

How is the moat score calculated?

Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.

Why is Exelixis, Inc. scored with the Corporate Default template?

Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.

Which competitive defenses are measured for Exelixis, Inc.?

The Corporate Default template measures 6 defenses, and EXEL scores: Pricing Power (85), Cost Advantage (95), Customer Stickiness (94), Capital Efficiency (88), Resilience (65), Scale & Market Position (68). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.

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