Lyra Therapeutics, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of anti-inflammatory therapies for the treatment of patients with chronic rhinosinusitis. Its technology is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix which is in Phase III clinical …
Full LYRA analysis →
Competitive advantage assessment
Key strengths
ROIC Sustainably Above PeersROIC at 96.2th percentile exceeds peers and WACC, demonstrating superior capital allocation.
Operating Leverage in EffectOperating leverage is evident (score 0.88), with margins expanding over time.
Lyra Therapeutics, Inc. ranks #380 of 713
scored companies in Biotechnology by moat score — the top 53%.
The widest moat in the group is Royalty Pharma plc (RPRX)
at 85/100.
Moat scores for companies ranked near LYRA in Biotechnology
Pricing power is the ability to raise prices without losing volume.
Cost Advantage
Score 16
· 15% of the moat score
A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.
Customer Stickiness
Score 25
· 15% of the moat score
Stickiness is what makes revenue repeat without being re-won every year.
Capital Efficiency
Score 68
· 18% of the moat score
Capital efficiency asks what the company earns on the money tied up in the business.
Resilience
Score 26
· 17% of the moat score
Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.
Scale & Market Position
Score 70
· 15% of the moat score
Scale matters only when it converts into economics.
Lyra Therapeutics, Inc. (LYRA) scores 39 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as developing. It ranks #380 of 713 scored companies in Biotechnology, the top 53%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Scale & Market Position (70/100) and its weakest is Cost Advantage (16/100).
How does Lyra Therapeutics, Inc. compare with other Biotechnology companies?
Lyra Therapeutics, Inc. ranks #380 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Trevi Therapeutics, Inc. (TRVI) at 39 just above it and Veru Inc. (VERU) at 39 just below it.
How is the moat score calculated?
Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.
Why is Lyra Therapeutics, Inc. scored with the Corporate Default template?
Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.
Which competitive defenses are measured for Lyra Therapeutics, Inc.?
The Corporate Default template measures 6 defenses, and LYRA scores: Pricing Power (29), Cost Advantage (16), Customer Stickiness (25), Capital Efficiency (68), Resilience (26), Scale & Market Position (70). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.
We value your privacy
We use cookies to enhance your browsing experience, analyze site traffic, and personalize content. By clicking 'Accept All', you consent to our use of cookies.
Read our cookie policy
Cookie Preferences
Manage your cookie preferences. Essential cookies are always enabled.