Northwest Biotherapeutics, Inc. NWBO

Competitive advantage analysis · healthcare

Corporate Default
Overall moat score
47/100
Developing

About Northwest Biotherapeutics, Inc.

Northwest Biotherapeutics, Inc., a biotechnology company, focuses on developing personalized immune therapies for cancer. The company develops DCVax, a platform technology that uses activated dendritic cells to mobilize a patient's own immune system to attack cancer. Its lead product candidate is the DCVax-L, which has completed Phase III clinical trials to treat Glioblastoma multiforme brain cancer. The company also develops … Full NWBO analysis →

Competitive advantage assessment

Key strengths

  • ROIC Sustainably Above Peers ROIC at 100.0th percentile exceeds peers and WACC, demonstrating superior capital allocation.
  • Strong Interest Coverage & Conservative Leverage Debt serviceability is strong (score 0.79), with robust interest coverage.

Key risks

  • Commodity Pressure / Weak Differentiation Gross margin at 0th percentile with high volatility suggests weak pricing power or commoditized products.
  • Below-Peer Operating Efficiency Operating margin at 24.7th percentile indicates below-peer efficiency.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

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Pricing Power

Developing
27

Where NWBO ranks in Biotechnology

Northwest Biotherapeutics, Inc. ranks #278 of 713 scored companies in Biotechnology by moat score — the top 39%. The widest moat in the group is Royalty Pharma plc (RPRX) at 85/100.

Moat scores for companies ranked near NWBO in Biotechnology
# Company Moat score Rating
274 Bright Minds Biosciences Inc. DRUG 47/100 Developing
275 Janux Therapeutics, Inc. JANX 47/100 Developing
276 Bolt Biotherapeutics, Inc. BOLT 47/100 Developing
277 Corvus Pharmaceuticals, Inc. CRVS 47/100 Developing
278 Northwest Biotherapeutics, Inc. NWBO 47/100 Developing
279 Gossamer Bio, Inc. GOSS 46/100 Developing
280 Aldeyra Therapeutics, Inc. ALDX 46/100 Developing
281 Centessa Pharmaceuticals plc CNTA 46/100 Developing
282 Dyne Therapeutics, Inc. DYN 46/100 Developing

See every Biotech / Pre-Revenue company ranked by moat score →

How NWBO scores on the Corporate Default defenses

Pricing Power

Score 27 · 20% of the moat score

Pricing power is the ability to raise prices without losing volume.

Cost Advantage

Score 20 · 15% of the moat score

A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.

Customer Stickiness

Score 47 · 15% of the moat score

Stickiness is what makes revenue repeat without being re-won every year.

Capital Efficiency

Score 95 · 18% of the moat score

Capital efficiency asks what the company earns on the money tied up in the business.

Resilience

Score 44 · 17% of the moat score

Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.

Scale & Market Position

Score 42 · 15% of the moat score

Scale matters only when it converts into economics.

How each Corporate Default defense is measured, in full →

Understanding NWBO's moat

What is Northwest Biotherapeutics, Inc.'s moat score?

Northwest Biotherapeutics, Inc. (NWBO) scores 46 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as developing. It ranks #278 of 713 scored companies in Biotechnology, the top 39%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Capital Efficiency (95/100) and its weakest is Cost Advantage (20/100).

How does Northwest Biotherapeutics, Inc. compare with other Biotechnology companies?

Northwest Biotherapeutics, Inc. ranks #278 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Corvus Pharmaceuticals, Inc. (CRVS) at 46 just above it and Gossamer Bio, Inc. (GOSS) at 46 just below it.

How is the moat score calculated?

Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.

Why is Northwest Biotherapeutics, Inc. scored with the Corporate Default template?

Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.

Which competitive defenses are measured for Northwest Biotherapeutics, Inc.?

The Corporate Default template measures 6 defenses, and NWBO scores: Pricing Power (27), Cost Advantage (20), Customer Stickiness (47), Capital Efficiency (95), Resilience (44), Scale & Market Position (42). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.

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