Skip to content

Spero Therapeutics, Inc. (SPRO) Company Overview

Company Analysis

Spero Therapeutics, Inc. SPRO

A comprehensive view of key metrics, scores, and financial health for Spero Therapeutics, Inc.

Overview of Spero Therapeutics, Inc.

SPRO NMS
Healthcare Biotechnology Framework: Biotech / Pre-Revenue Micro Cap
Spero Therapeutics, Inc. (SPRO), is a Micro Cap company, in the Biotechnology industry, last closed at $1.14, about 88.6% undervalued vs fair value, -52.1% 1Y return, ranked 422/1145 in sector.
Metrics P/E 16.0× Rev Growth 117.6% ROE 16.3%
USD 1.14
6.54%
(Delayed)
• Vol 90d: 73.7%
52-Week Range
Market Cap
$66.40M
Enterprise Value
$15.63M
Overall Score
Overall
Growth
Fair
Profitability
Good
Health
Fair
Efficiency
Good
Valuation
Good
Growth
Fair
Profitability
Good
Health
Fair
Efficiency
Good
Valuation
Good
Completeness: 76%
Confidence: 86%
Updated: Oct 24
Top Beats

Quick Facts

HQ Cambridge, MA
Employees 32
Fiscal year Dec 31

Next Events

Earnings Nov 12 Estimated

Fair Value Snapshot

Bear Base Bull
$2
$2
$2
Current: $1.14 +89% vs base

Engine Room Money Flow™

Micro Cap

Biotech / Pre-Revenue - Where revenue goes and how value is created

Flow Steps
Cash on Hand
$40.3M
-23.9%%
Total Revenue
$59.6M
117.6%%
Net Income
$8.6M
112.5%%
Operating Expense
$52.5M
-47.5%%
Money Flow Bridge
Flow Direction: Money moves from left to right
Components: Breakdown shows composition of each stage
Industry-Specific: Biotech / Pre-Revenue

Quality & Reliability Indicators

Cash Runway
38.3 months
Excellent

Strong cash position with 2+ years of runway

Locked Metric
-
Premium
Locked Metric
-
Premium
Locked Metric
-
Premium
Locked Metric
-
Premium
Locked Metric
-
Premium
Locked Metric
-
Premium
Locked Metric
-
Premium

Where It Leaks

Cash Flow Health critical
Significant cash flow inefficiencies identified. Multiple high-impact leaks require attention.
1
Active Leaks
0/1
Improving
0
High Impact
1
Critical
Moat Analysis Corporate Default

Competitive Advantage Assessment

Evaluating Spero Therapeutics, Inc.'s durable competitive advantages across 6 defense dimensions

Overall Moat Strength
64
/100
Moderate
Scores based on quantitative metrics and qualitative factors

Key strengths

  • ROIC Sustainably Above Peers ROIC at 84.8th percentile exceeds peers and WACC, demonstrating superior capital allocation.
  • Cost Leadership Position Operating margin at 89.7th percentile with strong OpEx control demonstrates cost leadership.

Key risks

  • Commodity Pressure / Weak Differentiation Gross margin at 10.4th percentile with high volatility suggests weak pricing power or commoditized products.
  • Revenue Volatility Signals Weak Stickiness Revenue volatility is high (stability score 0.17), suggesting weak customer stickiness.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

Upgrade to unlock the signals and evidence behind each defense.

Premium access

Unlock full defense analysis

Get key signals, strengths, and risks for every moat dimension.

Upgrade to Premium Unlock all moat defenses and evidence.

Pricing Power

Developing
34

Trade-Off Ledger™

Where management spends the performance budget - Growth, Profitability, or Safety

Pre-Revenue Biotech vs Industry Peers 67% Coverage
Trade-Off Triangle Visualization A ternary plot showing SPRO's balance between Growth (8.1%), Profitability (32.0%), and Safety (59.9%). Growth 8% Safety 60% Profitability 32%

Click axes to expand details. Marker shows current allocation.

3-Year Trend Analysis Locked
Upgrade to unlock the full 3-year trend analysis and deltas.

Growth

8th percentile vs peers
8
Key Signals
TSR -82.6% 8p
  • Strong liquidity position vs peers
  • Growth in bottom 20% of peers (percentile: 8)

Profitability

- vs peers
-
Key Signals
Strengths
Risks
Premium
Unlock full Profitability drilldowns

See the signal-level drivers and insights behind this axis. Upgrade to reveal the full Trade-Off Ledger.

Upgrade Now

Safety

62th percentile vs peers
62
Key Signals
Strengths
Safety drilldowns are available to premium members.

Two Futures

Scenario-based fair value ranges for Spero Therapeutics, Inc..

Loading scenario defaults...
Loading valuation model...
Unable to Compute Fair Value

This company cannot be valued using standard models.

What this means: The Scenario Theatre requires financial data (revenue, cash flow, shares outstanding) to calculate fair value estimates. This data may be unavailable for:

  • Recently listed companies (IPOs, SPACs)
  • Shell companies or holding companies
  • Companies that haven't filed recent financials
  • Foreign companies with limited data coverage
X.X%
X%XX%
X.X%
-XX%XX%
XX.X%
-XX%XX%
Adjust the sliders above to explore different valuation scenarios.
Unlock Premium
Reveal the full Scenario Theatre
See live sliders, narratives, and full Bear/Base/Bull outcomes.
Upgrade Now
Bear
-
- - -
- upside
-
Base
$2.15
- - -
+88.6% vs current
Snapshot base estimate
Bull
-
- - -
- upside
-
Fair Value Range Current: $-
$- $- $-
Actions & Info
Send Feedback
Please select a category.
0/1000