Actuate Therapeutics, Inc. ACTU

Competitive advantage analysis · healthcare

Corporate Default
Overall moat score
13/100
Weak

About Actuate Therapeutics, Inc.

Actuate Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops therapies for the treatment of cancers in the United States. The company's lead product candidate is elraglusib injection, a glycogen synthase kinase-3 inhibitor that is in Phase 2 trial to treat metastatic pancreatic ductal adenocarcinoma. It also develops elraglusib, which is in Phase 1/2 trial for the treatment of refractory pediatric malignancies, … Full ACTU analysis →

Competitive advantage assessment

Key risks

  • ROIC Below WACC or Peers ROIC at 8.6th percentile suggests inefficient capital deployment.
  • Elevated Debt Risk Debt serviceability is weak (score 0.12), raising refinancing risk.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

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Pricing Power

Insufficient Data
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Where ACTU ranks in Biotechnology

Actuate Therapeutics, Inc. ranks #634 of 713 scored companies in Biotechnology by moat score — the top 89%. The widest moat in the group is Royalty Pharma plc (RPRX) at 85/100.

Moat scores for companies ranked near ACTU in Biotechnology
# Company Moat score Rating
630 Clearmind Medicine Inc. CMND 13/100 Weak
631 InflaRx N.V. IFRX 13/100 Weak
632 GRI Bio, Inc. GRI 13/100 Weak
633 Reviva Pharmaceuticals Holdings RVPHW 13/100 Weak
634 Actuate Therapeutics, Inc. ACTU 13/100 Weak
635 Reviva Pharmaceuticals Holdings RVPH 12/100 Weak
636 Vincerx Pharma, Inc. VINC 12/100 Weak
637 Ensysce Biosciences, Inc. ENSC 12/100 Weak
638 Calidi Biotherapeutics, Inc. CLDI 12/100 Weak

See every Biotech / Pre-Revenue company ranked by moat score →

How ACTU scores on the Corporate Default defenses

Pricing Power

Not measurable · 20% of the moat score

Pricing power is the ability to raise prices without losing volume.

Cost Advantage

Not measurable · 15% of the moat score

A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.

Customer Stickiness

Not measurable · 15% of the moat score

Stickiness is what makes revenue repeat without being re-won every year.

Capital Efficiency

Score 9 · 18% of the moat score

Capital efficiency asks what the company earns on the money tied up in the business.

Resilience

Score 18 · 17% of the moat score

Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.

Scale & Market Position

Not measurable · 15% of the moat score

Scale matters only when it converts into economics.

How each Corporate Default defense is measured, in full →

Understanding ACTU's moat

What is Actuate Therapeutics, Inc.'s moat score?

Actuate Therapeutics, Inc. (ACTU) scores 13 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as weak. It ranks #634 of 713 scored companies in Biotechnology, the top 89%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Resilience (18/100) and its weakest is Capital Efficiency (9/100).

How does Actuate Therapeutics, Inc. compare with other Biotechnology companies?

Actuate Therapeutics, Inc. ranks #634 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Reviva Pharmaceuticals Holdings (RVPHW) at 13 just above it and Reviva Pharmaceuticals Holdings (RVPH) at 12 just below it.

How is the moat score calculated?

Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.

Why is Actuate Therapeutics, Inc. scored with the Corporate Default template?

Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.

Which competitive defenses are measured for Actuate Therapeutics, Inc.?

The Corporate Default template measures 6 defenses, and ACTU scores: Pricing Power (not measurable), Cost Advantage (not measurable), Customer Stickiness (not measurable), Capital Efficiency (9), Resilience (18), Scale & Market Position (not measurable). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.

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