Applied Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development of a pipeline of novel product candidates against validated molecular targets in indications of high unmet medical need in the United States. The company's lead product candidate is AT-007 that has completed phase 3 for the treatment of galactosemia in healthy volunteers and adults, in pediatric clinical study for …
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Competitive advantage assessment
Key risks
Commodity Pressure / Weak DifferentiationGross margin at 1.9th percentile with high volatility suggests weak pricing power or commoditized products.
ROIC Below WACC or PeersROIC at 16.5th percentile suggests inefficient capital deployment.
The dashed ring is the peer median. Defense scores are percentile ranks
against peers, so 50 is roughly the typical company in this group.
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Applied Therapeutics, Inc. ranks #639 of 713
scored companies in Biotechnology by moat score — the top 90%.
The widest moat in the group is Royalty Pharma plc (RPRX)
at 85/100.
Moat scores for companies ranked near APLT in Biotechnology
Pricing power is the ability to raise prices without losing volume.
Cost Advantage
Score 9
· 15% of the moat score
A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.
Customer Stickiness
Score 12
· 15% of the moat score
Stickiness is what makes revenue repeat without being re-won every year.
Capital Efficiency
Score 6
· 18% of the moat score
Capital efficiency asks what the company earns on the money tied up in the business.
Resilience
Score 26
· 17% of the moat score
Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.
Scale & Market Position
Score 7
· 15% of the moat score
Scale matters only when it converts into economics.
Applied Therapeutics, Inc. (APLT) scores 12 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as weak. It ranks #639 of 713 scored companies in Biotechnology, the top 90%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Resilience (26/100) and its weakest is Pricing Power (3/100).
How does Applied Therapeutics, Inc. compare with other Biotechnology companies?
Applied Therapeutics, Inc. ranks #639 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Calidi Biotherapeutics, Inc. (CLDI) at 12 just above it and BioCardia, Inc. (BCDA) at 12 just below it.
How is the moat score calculated?
Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.
Why is Applied Therapeutics, Inc. scored with the Corporate Default template?
Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.
Which competitive defenses are measured for Applied Therapeutics, Inc.?
The Corporate Default template measures 6 defenses, and APLT scores: Pricing Power (3), Cost Advantage (9), Customer Stickiness (12), Capital Efficiency (6), Resilience (26), Scale & Market Position (7). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.
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