Foghorn Therapeutics Inc. FHTX

Competitive advantage analysis · healthcare

Corporate Default
Overall moat score
57/100
Moderate

About Foghorn Therapeutics Inc.

Foghorn Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of medicines targeting genetically determined dependencies within the chromatin regulatory system in the United States. The company uses its proprietary Gene Traffic Control platform to identify, validate, and potentially drug targets within the system. It is also developing therapies for mutant cancers, such as androgen receptor, positive … Full FHTX analysis →

Competitive advantage assessment

Key strengths

  • ROIC Sustainably Above Peers ROIC at 91.4th percentile exceeds peers and WACC, demonstrating superior capital allocation.
  • Scale Supporting Profitability Profitability at scale is strong (score 0.80), demonstrating competitive advantages.

Key risks

  • Elevated Debt Risk Debt serviceability is weak (score 0.00), raising refinancing risk.
  • Revenue Volatility Signals Weak Stickiness Revenue volatility is high (stability score 0.20), suggesting weak customer stickiness.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

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Pricing Power

Developing
37

Where FHTX ranks in Biotechnology

Foghorn Therapeutics Inc. ranks #140 of 713 scored companies in Biotechnology by moat score — the top 20%. The widest moat in the group is Royalty Pharma plc (RPRX) at 85/100.

Moat scores for companies ranked near FHTX in Biotechnology
# Company Moat score Rating
136 Invivyd, Inc. IVVD 58/100 Moderate
137 Protagonist Therapeutics, Inc. PTGX 58/100 Moderate
138 Conduit Pharmaceuticals Inc. CDT 58/100 Moderate
139 Phathom Pharmaceuticals, Inc. PHAT 58/100 Moderate
140 Foghorn Therapeutics Inc. FHTX 57/100 Moderate
141 Fortrea Holdings Inc. FTRE 57/100 Moderate
142 Dominari Holdings Inc. DOMH 57/100 Moderate
143 Zevra Therapeutics, Inc. ZVRA 57/100 Moderate
144 C4 Therapeutics, Inc. CCCC 57/100 Moderate

See every Biotech / Pre-Revenue company ranked by moat score →

How FHTX scores on the Corporate Default defenses

Pricing Power

Score 37 · 20% of the moat score

Pricing power is the ability to raise prices without losing volume.

Cost Advantage

Score 65 · 15% of the moat score

A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.

Customer Stickiness

Score 43 · 15% of the moat score

Stickiness is what makes revenue repeat without being re-won every year.

Capital Efficiency

Score 73 · 18% of the moat score

Capital efficiency asks what the company earns on the money tied up in the business.

Resilience

Score 43 · 17% of the moat score

Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.

Scale & Market Position

Score 83 · 15% of the moat score

Scale matters only when it converts into economics.

How each Corporate Default defense is measured, in full →

Understanding FHTX's moat

What is Foghorn Therapeutics Inc.'s moat score?

Foghorn Therapeutics Inc. (FHTX) scores 57 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as moderate. It ranks #140 of 713 scored companies in Biotechnology, the top 20%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Scale & Market Position (83/100) and its weakest is Pricing Power (37/100).

How does Foghorn Therapeutics Inc. compare with other Biotechnology companies?

Foghorn Therapeutics Inc. ranks #140 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Phathom Pharmaceuticals, Inc. (PHAT) at 58 just above it and Fortrea Holdings Inc. (FTRE) at 57 just below it.

How is the moat score calculated?

Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.

Why is Foghorn Therapeutics Inc. scored with the Corporate Default template?

Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.

Which competitive defenses are measured for Foghorn Therapeutics Inc.?

The Corporate Default template measures 6 defenses, and FHTX scores: Pricing Power (37), Cost Advantage (65), Customer Stickiness (43), Capital Efficiency (73), Resilience (43), Scale & Market Position (83). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.

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