Zevra Therapeutics, Inc. ZVRA

Competitive advantage analysis · healthcare

Corporate Default
Overall moat score
57/100
Moderate

About Zevra Therapeutics, Inc.

Zevra Therapeutics, Inc., a commercial-stage company, focuses on addressing unmet needs for the treatment of rare diseases in the United States. The company develops its products through Ligand Activated Technology platform. Its lead product candidate is KP1077, consisting of KP1077IH, which is under Phase 2 clinical trial for the treatment of idiopathic hypersomnia, and KP1077N, which is under Phase 1/2 … Full ZVRA analysis →

Competitive advantage assessment

Key strengths

  • Consistent Cash Generation Cash generation is strong and consistent (score 0.86).
  • Cost Leadership Position Operating margin at 76.5th percentile with strong OpEx control demonstrates cost leadership.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

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Pricing Power

Developing
47

Where ZVRA ranks in Biotechnology

Zevra Therapeutics, Inc. ranks #143 of 713 scored companies in Biotechnology by moat score — the top 20%. The widest moat in the group is Royalty Pharma plc (RPRX) at 85/100.

Moat scores for companies ranked near ZVRA in Biotechnology
# Company Moat score Rating
139 Phathom Pharmaceuticals, Inc. PHAT 58/100 Moderate
140 Foghorn Therapeutics Inc. FHTX 57/100 Moderate
141 Fortrea Holdings Inc. FTRE 57/100 Moderate
142 Dominari Holdings Inc. DOMH 57/100 Moderate
143 Zevra Therapeutics, Inc. ZVRA 57/100 Moderate
144 C4 Therapeutics, Inc. CCCC 57/100 Moderate
145 Grace Therapeutics, Inc. GRCE 57/100 Moderate
146 Nektar Therapeutics NKTR 57/100 Moderate
147 NeuroSense Therapeutics Ltd. NRSN 57/100 Moderate

See every Biotech / Pre-Revenue company ranked by moat score →

How ZVRA scores on the Corporate Default defenses

Pricing Power

Score 47 · 20% of the moat score

Pricing power is the ability to raise prices without losing volume.

Cost Advantage

Score 74 · 15% of the moat score

A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.

Customer Stickiness

Score 68 · 15% of the moat score

Stickiness is what makes revenue repeat without being re-won every year.

Capital Efficiency

Score 40 · 18% of the moat score

Capital efficiency asks what the company earns on the money tied up in the business.

Resilience

Score 66 · 17% of the moat score

Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.

Scale & Market Position

Score 53 · 15% of the moat score

Scale matters only when it converts into economics.

How each Corporate Default defense is measured, in full →

Understanding ZVRA's moat

What is Zevra Therapeutics, Inc.'s moat score?

Zevra Therapeutics, Inc. (ZVRA) scores 57 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as moderate. It ranks #143 of 713 scored companies in Biotechnology, the top 20%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Cost Advantage (74/100) and its weakest is Capital Efficiency (40/100).

How does Zevra Therapeutics, Inc. compare with other Biotechnology companies?

Zevra Therapeutics, Inc. ranks #143 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Dominari Holdings Inc. (DOMH) at 57 just above it and C4 Therapeutics, Inc. (CCCC) at 57 just below it.

How is the moat score calculated?

Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.

Why is Zevra Therapeutics, Inc. scored with the Corporate Default template?

Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.

Which competitive defenses are measured for Zevra Therapeutics, Inc.?

The Corporate Default template measures 6 defenses, and ZVRA scores: Pricing Power (47), Cost Advantage (74), Customer Stickiness (68), Capital Efficiency (40), Resilience (66), Scale & Market Position (53). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.

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