Lexicon Pharmaceuticals, Inc. LXRX

Competitive advantage analysis · healthcare

Corporate Default
Overall moat score
53/100
Moderate

About Lexicon Pharmaceuticals, Inc.

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company offers Sotagliflozin, an orally-delivered small molecule drug to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visits in adults with heart failure or type 2 diabetes mellitus, chronic kidney disease … Full LXRX analysis →

Competitive advantage assessment

Key strengths

  • Strong Interest Coverage & Conservative Leverage Debt serviceability is strong (score 0.80), with robust interest coverage.
  • Operating Leverage in Effect Operating leverage is evident (score 0.95), with margins expanding over time.

Key risks

  • Revenue Volatility Signals Weak Stickiness Revenue volatility is high (stability score 0.11), suggesting weak customer stickiness.
  • Volatile Margins Suggest Cyclicality Margin volatility is high (stability score 0.12), suggesting cyclical exposure or competitive pressure.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

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Pricing Power

Developing
25

Where LXRX ranks in Biotechnology

Lexicon Pharmaceuticals, Inc. ranks #201 of 713 scored companies in Biotechnology by moat score — the top 28%. The widest moat in the group is Royalty Pharma plc (RPRX) at 85/100.

Moat scores for companies ranked near LXRX in Biotechnology
# Company Moat score Rating
197 Maravai LifeSciences Holdings, MRVI 53/100 Moderate
198 Zentalis Pharmaceuticals, Inc. ZNTL 53/100 Moderate
199 Arcus Biosciences, Inc. RCUS 53/100 Moderate
200 Cyclerion Therapeutics, Inc. CYCN 53/100 Moderate
201 Lexicon Pharmaceuticals, Inc. LXRX 53/100 Moderate
202 Cassava Sciences, Inc. SAVA 53/100 Moderate
203 Curis, Inc. CRIS 53/100 Moderate
204 Evogene Ltd. EVGN 53/100 Moderate
205 Voyager Therapeutics, Inc. VYGR 53/100 Moderate

See every Biotech / Pre-Revenue company ranked by moat score →

How LXRX scores on the Corporate Default defenses

Pricing Power

Score 25 · 20% of the moat score

Pricing power is the ability to raise prices without losing volume.

Cost Advantage

Score 72 · 15% of the moat score

A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.

Customer Stickiness

Score 45 · 15% of the moat score

Stickiness is what makes revenue repeat without being re-won every year.

Capital Efficiency

Score 38 · 18% of the moat score

Capital efficiency asks what the company earns on the money tied up in the business.

Resilience

Score 69 · 17% of the moat score

Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.

Scale & Market Position

Score 79 · 15% of the moat score

Scale matters only when it converts into economics.

How each Corporate Default defense is measured, in full →

Understanding LXRX's moat

What is Lexicon Pharmaceuticals, Inc.'s moat score?

Lexicon Pharmaceuticals, Inc. (LXRX) scores 53 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as moderate. It ranks #201 of 713 scored companies in Biotechnology, the top 28%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Scale & Market Position (79/100) and its weakest is Pricing Power (25/100).

How does Lexicon Pharmaceuticals, Inc. compare with other Biotechnology companies?

Lexicon Pharmaceuticals, Inc. ranks #201 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Cyclerion Therapeutics, Inc. (CYCN) at 53 just above it and Cassava Sciences, Inc. (SAVA) at 53 just below it.

How is the moat score calculated?

Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.

Why is Lexicon Pharmaceuticals, Inc. scored with the Corporate Default template?

Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.

Which competitive defenses are measured for Lexicon Pharmaceuticals, Inc.?

The Corporate Default template measures 6 defenses, and LXRX scores: Pricing Power (25), Cost Advantage (72), Customer Stickiness (45), Capital Efficiency (38), Resilience (69), Scale & Market Position (79). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.

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