Voyager Therapeutics, Inc. VYGR

Competitive advantage analysis · healthcare

Corporate Default
Overall moat score
53/100
Moderate

About Voyager Therapeutics, Inc.

Voyager Therapeutics, Inc., a biotechnology company, focuses on the human genetics for the cure of neurological diseases. The company's lead product candidate is VY7523, an anti-tau antibody program for the treatment of alzheimer's disease (AD). Its product pipeline includes VY1706, a tau silencing gene therapy in preclinical trial for the treatment of alzheimer's disease; SOD1 silencing gene therapy program for … Full VYGR analysis →

Competitive advantage assessment

Key strengths

  • Margins Stable Across Cycles Operating margin volatility is low (stability score 0.78), demonstrating pricing resilience across cycles.
  • Scale Supporting Profitability Profitability at scale is strong (score 0.79), demonstrating competitive advantages.

Key risks

  • Revenue Volatility Signals Weak Stickiness Revenue volatility is high (stability score 0.32), suggesting weak customer stickiness.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

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Pricing Power

Moderate
55

Where VYGR ranks in Biotechnology

Voyager Therapeutics, Inc. ranks #205 of 713 scored companies in Biotechnology by moat score — the top 29%. The widest moat in the group is Royalty Pharma plc (RPRX) at 85/100.

Moat scores for companies ranked near VYGR in Biotechnology
# Company Moat score Rating
201 Lexicon Pharmaceuticals, Inc. LXRX 53/100 Moderate
202 Cassava Sciences, Inc. SAVA 53/100 Moderate
203 Curis, Inc. CRIS 53/100 Moderate
204 Evogene Ltd. EVGN 53/100 Moderate
205 Voyager Therapeutics, Inc. VYGR 53/100 Moderate
206 Atea Pharmaceuticals, Inc. AVIR 52/100 Moderate
207 Anavex Life Sciences Corp. AVXL 52/100 Moderate
208 NovaBay Pharmaceuticals, Inc. NBY 52/100 Moderate
209 PepGen Inc. PEPG 52/100 Moderate

See every Biotech / Pre-Revenue company ranked by moat score →

How VYGR scores on the Corporate Default defenses

Pricing Power

Score 55 · 20% of the moat score

Pricing power is the ability to raise prices without losing volume.

Cost Advantage

Score 63 · 15% of the moat score

A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.

Customer Stickiness

Score 47 · 15% of the moat score

Stickiness is what makes revenue repeat without being re-won every year.

Capital Efficiency

Score 32 · 18% of the moat score

Capital efficiency asks what the company earns on the money tied up in the business.

Resilience

Score 57 · 17% of the moat score

Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.

Scale & Market Position

Score 64 · 15% of the moat score

Scale matters only when it converts into economics.

How each Corporate Default defense is measured, in full →

Understanding VYGR's moat

What is Voyager Therapeutics, Inc.'s moat score?

Voyager Therapeutics, Inc. (VYGR) scores 52 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as moderate. It ranks #205 of 713 scored companies in Biotechnology, the top 29%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Scale & Market Position (64/100) and its weakest is Capital Efficiency (32/100).

How does Voyager Therapeutics, Inc. compare with other Biotechnology companies?

Voyager Therapeutics, Inc. ranks #205 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Evogene Ltd. (EVGN) at 53 just above it and Atea Pharmaceuticals, Inc. (AVIR) at 52 just below it.

How is the moat score calculated?

Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.

Why is Voyager Therapeutics, Inc. scored with the Corporate Default template?

Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.

Which competitive defenses are measured for Voyager Therapeutics, Inc.?

The Corporate Default template measures 6 defenses, and VYGR scores: Pricing Power (55), Cost Advantage (63), Customer Stickiness (47), Capital Efficiency (32), Resilience (57), Scale & Market Position (64). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.

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