Achilles Therapeutics plc ACHL

Competitive advantage analysis · healthcare

Corporate Default
Overall moat score
58/100
Moderate

Ranked against 712 peers in Biotechnology

Key strengths

  • Strong Interest Coverage & Conservative Leverage Debt serviceability is strong (score 0.72), with robust interest coverage.
  • Strong Liquidity Buffer Liquidity position is strong (score 0.74), providing operational cushion.

Key risks

  • ROIC Below WACC or Peers ROIC at 0th percentile suggests inefficient capital deployment.
  • Weak or Negative Cash Flow Cash generation is weak (score 0.00), limiting financial flexibility.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

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Pricing Power

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Signals, strengths and risks for Pricing Power

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Signals, strengths and risks for Cost Advantage

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Signals, strengths and risks for Customer Stickiness

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Signals, strengths and risks for Capital Efficiency

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Signals, strengths and risks for Resilience

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Signals, strengths and risks for Scale & Market Position

Where ACHL ranks in Biotechnology

Achilles Therapeutics plc ranks #124 of 713 scored companies in Biotechnology by moat score — the top 17%. The widest moat in the group is Royalty Pharma plc (RPRX) at 85/100.

# Company Moat score Rating
120 BriaCell Therapeutics Corp. BCTX 59/100 Moderate
121 BriaCell Therapeutics Corp. BCTXW 59/100 Moderate
122 Day One Biopharmaceuticals, Inc DAWN 59/100 Moderate
123 ImmunityBio, Inc. IBRX 59/100 Moderate
124 Achilles Therapeutics plc ACHL 58/100 Moderate
125 Agenus Inc. AGEN 58/100 Moderate
126 Precision BioSciences, Inc. DTIL 58/100 Moderate
127 Structure Therapeutics Inc. GPCR 58/100 Moderate
128 Cullinan Therapeutics, Inc. CGEM 58/100 Moderate

See every Biotech / Pre-Revenue company ranked by moat score →

How ACHL scores on the Corporate Default defenses

Pricing Power

Not measurable · 20% of the moat score

Pricing power is the ability to raise prices without losing volume.

Cost Advantage

Not measurable · 15% of the moat score

A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.

Customer Stickiness

Not measurable · 15% of the moat score

Stickiness is what makes revenue repeat without being re-won every year.

Capital Efficiency

Score 49 · 18% of the moat score

Capital efficiency asks what the company earns on the money tied up in the business.

Resilience

Score 73 · 17% of the moat score

Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.

Scale & Market Position

Not measurable · 15% of the moat score

Scale matters only when it converts into economics.

How each Corporate Default defense is measured, in full →

Understanding ACHL's moat

What is Achilles Therapeutics plc's moat score?

Achilles Therapeutics plc (ACHL) scores 58 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as moderate. It ranks #124 of 713 scored companies in Biotechnology, the top 17%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Resilience (73/100) and its weakest is Capital Efficiency (49/100).

How does Achilles Therapeutics plc compare with other Biotechnology companies?

Achilles Therapeutics plc ranks #124 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are ImmunityBio, Inc. (IBRX) at 59 just above it and Agenus Inc. (AGEN) at 58 just below it.

How is the moat score calculated?

Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.

Why is Achilles Therapeutics plc scored with the Corporate Default template?

Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.

Which competitive defenses are measured for Achilles Therapeutics plc?

The Corporate Default template measures 6 defenses, and ACHL scores: Pricing Power (not measurable), Cost Advantage (not measurable), Customer Stickiness (not measurable), Capital Efficiency (49), Resilience (73), Scale & Market Position (not measurable). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.

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