Agenus Inc. AGEN

Competitive advantage analysis · healthcare

Corporate Default
Overall moat score
58/100
Moderate

About Agenus Inc.

Agenus Inc., a clinical-stage biotechnology company, discovers and develops therapies to activate the body's immune system against cancer and infections in the United States and internationally. It offers Retrocyte Display, an antibody expression platform for the identification of fully human and humanized monoclonal antibodies; and display technologies. It develops QS-21 Stimulon adjuvant, a saponin-based vaccine adjuvant. The company also develops … Full AGEN analysis →

Competitive advantage assessment

Key strengths

  • Cost Leadership Position Operating margin at 82.3th percentile with strong OpEx control demonstrates cost leadership.
  • ROIC Sustainably Above Peers ROIC at 84.0th percentile exceeds peers and WACC, demonstrating superior capital allocation.

Key risks

  • Liquidity Concerns Liquidity is concerning (score 0.06), raising questions about short-term obligations.

The dashed ring is the peer median. Defense scores are percentile ranks against peers, so 50 is roughly the typical company in this group.

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Pricing Power

Developing
49

Where AGEN ranks in Biotechnology

Agenus Inc. ranks #125 of 713 scored companies in Biotechnology by moat score — the top 18%. The widest moat in the group is Royalty Pharma plc (RPRX) at 85/100.

Moat scores for companies ranked near AGEN in Biotechnology
# Company Moat score Rating
121 BriaCell Therapeutics Corp. BCTXW 59/100 Moderate
122 Day One Biopharmaceuticals, Inc DAWN 59/100 Moderate
123 ImmunityBio, Inc. IBRX 59/100 Moderate
124 Achilles Therapeutics plc ACHL 58/100 Moderate
125 Agenus Inc. AGEN 58/100 Moderate
126 Precision BioSciences, Inc. DTIL 58/100 Moderate
127 Structure Therapeutics Inc. GPCR 58/100 Moderate
128 Cullinan Therapeutics, Inc. CGEM 58/100 Moderate
129 IDEAYA Biosciences, Inc. IDYA 58/100 Moderate

See every Biotech / Pre-Revenue company ranked by moat score →

How AGEN scores on the Corporate Default defenses

Pricing Power

Score 49 · 20% of the moat score

Pricing power is the ability to raise prices without losing volume.

Cost Advantage

Score 82 · 15% of the moat score

A cost advantage means delivering the same product for structurally less — better purchasing, denser distribution, a more automated process.

Customer Stickiness

Score 64 · 15% of the moat score

Stickiness is what makes revenue repeat without being re-won every year.

Capital Efficiency

Score 62 · 18% of the moat score

Capital efficiency asks what the company earns on the money tied up in the business.

Resilience

Score 45 · 17% of the moat score

Resilience is the capacity to get through a bad year on its own terms — enough liquidity, enough interest cover, and enough cash generation to avoid a rescue financing or a forced sale.

Scale & Market Position

Score 52 · 15% of the moat score

Scale matters only when it converts into economics.

How each Corporate Default defense is measured, in full →

Understanding AGEN's moat

What is Agenus Inc.'s moat score?

Agenus Inc. (AGEN) scores 58 out of 100 on the StatsAlpha Moat Map, which rates its competitive advantage as moderate. It ranks #125 of 713 scored companies in Biotechnology, the top 18%. The score is a weighted composite of 6 competitive defenses, each measured against industry peers of 712 companies in Biotechnology. Its strongest defense is Cost Advantage (82/100) and its weakest is Resilience (45/100).

How does Agenus Inc. compare with other Biotechnology companies?

Agenus Inc. ranks #125 of 713 scored companies in Biotechnology by moat score. The widest moat in Biotechnology is Royalty Pharma plc (RPRX) at 85/100. The companies ranked closest are Achilles Therapeutics plc (ACHL) at 58 just above it and Precision BioSciences, Inc. (DTIL) at 58 just below it.

How is the moat score calculated?

Each company is scored with an industry-specific template — Corporate Default in this case, chosen because the defenses that matter to a bank are not the ones that matter to a software company. Every defense combines several financial signals, and each signal is measured as a percentile against a peer group of 712 companies in Biotechnology. The defenses are then weighted to produce the overall score out of 100.

Why is Agenus Inc. scored with the Corporate Default template?

Most public companies sell a product or a service at a margin, so the moat question is whether that margin survives contact with competitors. The Corporate template scores the six defenses that show up in a general operating company's financial signature: whether it can hold price, produce more cheaply than rivals, keep its customers, earn a return above its cost of capital, withstand a downturn, and turn size into economics.

Which competitive defenses are measured for Agenus Inc.?

The Corporate Default template measures 6 defenses, and AGEN scores: Pricing Power (49), Cost Advantage (82), Customer Stickiness (64), Capital Efficiency (62), Resilience (45), Scale & Market Position (52). Each is scored independently as a percentile against peers, so a company can be strong on one and weak on another — the overall score reflects how those defenses are weighted for this industry.

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